There are benefits to each weapon, I know from experience.
Playing mostly PvE, I started with the sword and was amazed how much damage a Sever Artery/Gash/Galrath Slash/Final Thrust combo did. When the NPC tried to heal, I would Savage Slash to interrupt and repeat. Killing NPC's was fast, and I still had 3 skills slots open!
Then when I got to the Desert I found a nice Axe, so I switched and started using a nice Eviscerate/Executioners Strike/Swift Chop combo, with a Disrupting Chop at the ready. This was all about adrenaline though, so I took "For Great Justice" and Cyclone Axe too, and this left me 2 empty slots.
Then it was on to PvP, where neither my sword or axe builds seemed to work well, so I went and found a hammer.
Using "For Great Justice" and all attack skills, I found my hammer to be worthy in PvE as well, so I made sure I collected all the hammer skills, and it was on to PvP, again, my builds didn't seem too effective, but now at least I was causing a ruckus, spending most of my time using Balanced Stance so no one could knock me down, and waiting for Backbreaker to charge. Nice elite, that, +21 damage and it knocks down the opponent for 4 seconds. Can't do anything to me while they lie on the ground, so I always wait until Crushing Blow is ready too, thus hitting for +21 again, and now they've got a Deep Wound too. With Irresistible Blow, I also have an attack that cannot be evaded, and knocks down if its blocked.
So, the greatest part is, its all up to you! That's what I think makes this game great. Plus, after ascending and being able to choose any secondary, it leaves the warrior with a ton of playable options.
My current "Pure Warrior" build (PvE), doesn't matter what secondary profession:
Hammer Mastery: 12+3+1
Strength: 9+1
Tactics: 9+1
"For Great Justice"
Backbreaker
Crushing Blow
Irresistible Blow
Sprint
Balanced Stance
Endure Pain
Healing Signet
This build is ineffective if you are suffering from blind. LOL!