according to the little weapon modifiers thing over at gwonline, a wand/weapon can't 'spawn' with a - health mod, but foci can.
hmm... but that doesn't rule out finding a wand/weapon from a quest that has a -health mod, right?
It's not actually a weapon that you get from the Cities of Ascalon quest but a -50HP offhand item. It's tied to Necro Blood Magic, but you can still get +3 energy with it and it has a number of +energy modifiers as well. As far as a weapon with -HP, I haven't seen one.
yeah I've got that thing, and 55 health, but thats not good enough I want 35... so either a focus that does -70 or a wand that does -20... either will be good