The Dragons will undoubtedly take absolute control over whatever territories they make their homes in. These monsters are like.. anti-Gods.
Well, for every group of good guys, there's going to be an insanely powerful bad one. (Abaddon)
But for every group of bad guys, there's going to be a pathetically weak good one.
I can imagine one of the dragons making a utopia deep inside of its destroyed wasteland of woe. He may not be entirely good (eating random servants, demanding absurd tasks, etc.), but may recognize the main character as a worthy/interesting specimen, out of benevolence/boredom.
This may lead to the "Dragon Wars" XD
Cantha, shrouded in mystery, completely isolated... etc. May end up as a great miserable city of chaos, pain and fear. I can imagine ANet taking a piece of communist history and slapping "Cantha" all over it.
On the other hand, this string of Canthan emperors forcing unity and isolation could be the start of a technological/knowledge revolution of sorts. Imagine the renaissance taking place in this locked up country; The warring states have been united, so the people may not have much else to do besides grow and think and work. 250 years is a long time. There's an immense difference between 1758 and 2008. Personally, I don't want to see any goddamn'd computers in my Guild Wars... But, whatever. It's not completely out there. =]
Palawa Joko is another odd variable. This guy is the scourge of vabbi, yes, but I can imagine him maintaining a relatively powerful and productive country, despite his selfish demonic ways. I can see a mutual hatred between him and the Crystal Desert's dragon arise; Joko's legion of undead fighting the Desert Dragon's horde of demonic dragon spawns. A constant struggle for ownership over the desolation.
Finally, there's the rift. I'm -really- looking forward to revisiting the Fissure of Woe and the Underworld. 250 years ago, your character repelled Menzies' forces, and restored order to the Underworld. The Fissure's patches of grass will probably spread all over, and the volcanic activity may cease. Would it be too unlikely for humans to make their escape and settle for this relatively peaceful land? I'm sure the Ghostly heroes wouldn't mind some company.
What about the underworld? Without all of those damn Terrorwebs, I bet the spirits will end up constructing cities around Grenth's domain. It could be like Bleach's Soul Society.
M

