I'm a fan of using less commonly used things (in some cases more used = better, in others its just more used = easier to slam on one key and win) that have potential. I created this build with synergy in mind, each piece seems to fit nicely together.
Dagger Mastery - 16 (14 is an option if you don't like -75 HP)
Critical Strikes - 13 (12+1)
Deadly Arts - 4 (3+1)
Template Code: OwBj0xezIPKQycCbhhwogDQBAA
[skill]Seeping Wound[/skill][skill]black spider strike[/skill][skill]Horns of the Ox[/skill][skill]Black Lotus Strike[/skill][skill]Twisting Fangs[/skill][skill]Dark Prison[/skill][skill]Critical Defenses[/skill][skill]resurrection signet[/skill]
The objective of this build is high pressure. In optimal situations you can maintain -11 Degen and Deep Wound. In a straight forward RA you would cast Seeping Wound, Shadow Step to the enemy and use Black Spider Strike.
At that point you have 8 Degen on them. You continue with Horns of the Ox, giving them little time to react to the conditions/hex's. Follow up with Black Lotus Strike to fill up your E-Bar and land a Twisting Fangs at the perfect timing. Your opponent will be loaded with degen, and deep wounds. Critical Defenses can be kept up at all times to make melee not an issue.
Weaknesses
Hex Removal [However, Seeping Wound's cool down is fairly small so this isn't a huge disadvantage]
Condition Removal
Typical Anti-Melee Hex's/Conditions
No self heal
Variations:
Dark Prison and Resurrection Signet are not necessary and can be replaced by any of the following.
[skill]Disrupting Dagger[/skill][skill]Crippling Dagger[/skill][skill]Expose Defenses[/skill][skill]Signet of Malice[/skill][skill]Signet of Twilight[/skill]
If you chose to take out Dark Prison you can take the 3+1 from Deadly Arts and move it to Shadow Arts and take Shadow Refuge to keep yourself fueled with Regen. Its a pretty flexible build with a lot of options, and tends to be a great option in places where Hex/Condition is scarce (Such as RA).
If you have a chance try it out, I think you might like it.
C

It says "Spike" yet you say pressure is the main objective.