I have it, but I've only used it about 5 or 6 times.
The Nitrous was the first thing I tried, since it was the shortest, and it was the weirdest sensation ever. I was laughing and crying uncontrollably at the same time, and I couldn't really control my body at all. I also used the QuickHappy one, or whatever its called after the Giants beat my Packers in the Championship game, and I think it worked, but it might have just been a placebo.
I've tried LSD and marijuana and stuff and it had no effect.
It's either really hit or miss, or its a placebo.
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