Nightstalkers...
The Versus Slashing / Piercing / Blunt ones are all but worthless unless you're in a VERY exclusive environment or taking on a VERY particular kind of physical-attack foe... And since sins are for taking down squishies with priority, that is generally a no-no.
Radiant (or "Shrouded" to use its old name, which I prefer) is nice if you're casting or using a very energy-intensive build.... but generally if your Critical Strikes are high enough and you're using Zealous daggers then a large energy pool is a waste...
Survivor? Meh. As long as you have enough health to avoid being spiked to death, raising armour seems higher priority. Fine if you're using it to counter the effects of heavy rune usage...
But I swear by Nightstalker.
+15 Armour while attacking... and generally an Assassin is either attacking or not in the combat area at all. It might as well be unconditional for all the difference it makes.
Runes?
I'm a bit of a nutter in that I use two Major runes... one for Dagger Mastery and one for Critical Strikes. It ensures I can maintain both at a reasonably high level (At least 13) while maintaining a few points for Shadow Arts (Way of Perfection).
Superior Vigor is a must, unless you're seriously poor...
At least Minor Shadow Arts is recommended.
The other runes? Vitae or Attunement as you like it.
Appearance?
Whatever skin you like....
.... except Ancient. Nothing justifies Porcupine-Armour.
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