OK, you have to work out what it is you're trying to achieve with your Mesmer.
First off, decide whether you really need 16 in Domination, or whether you can drop it down a bit (but still retain energy burn at 10 points) and use the points elsewhere (i.e. getting Blood to 12).
You have 3 interrupts, which is nice, but you're also casting fairly long-CC spells like Shadow Strike, so just bear in mind that you'll have to be on the ball to get your damage in as well as your countering.
Going through your spells:
1. Dark Pact
2. Vampiric Gaze
3. Shadow Strike
These are the standard 3 spells that comprise the Blood spike. I suggest swapping spots so it goes SS/DP/VG, which is more conducive to casting in order. The standard sequence of SS/DP/VG/DP for 188 damage costs 30 energy, which doesn't leave you much left over.
4. Power Spike
Nice; low cost and cooldown, and reinforces your damage theme.
5. Power Leak
Perhaps not so nice. You already have a general-purpose interrupt, but unless you're targeting monks, you'll shut down the enemy instead of killing him. I'd rather take Shatter Enchantment, for those who drop Breeze or Prot anti-spike spells.
6. Power Block
A useful spell, but I don't think this elite fits in this build. I'd rather take Order of Blood to fill up the Necro Spiking engine.
7. Energy Burn
I suppose. It's decent damage for the cost. However, just bear in mind that you have nothing that interrupts signets, so you'll just have to do that damage all over again once they use a rez signet.
8. Ressurection Signet
"A must".
So, you would now have 4 spiking damage spells, 1 spiking interrupt, 1 anti-enchant spike, 1 energy regen spell (which should be enough), and a rez. Note that you're going to worry about healing a fair bit since your spells can steal life but probably not keep up with your Pacts, and you have absolutely nothing to scare a Warrior.
You might like to look at some other Necro spells (and elites) to see if there's anything that would be good, except for a slow casting time - these are the ones that benefit the most from your fast-cast.
(Personally, I would have gone for a stand-off Necro/Mesmer using blood, curses and inspiration, but to each her own).
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