Hi, I just wanted to return back to the original topic because I have had this question myself and have experimented with both Mo/Me and Me/Mo.
In my opinion, Mo/Me is pretty good if you're going to be the healer, seeing as you can then have inspiration into it, which allows you to get some extra energy. The problem I had with that idea is that you're pretty much not a damage dealer, since I devoted the other 2 attribute focuses to healing and divine. I'm not much a fan of smiting since most of the skills do fairly small damage and take long times to cast/recharge, plus they don't really have fantastic effects except when against undead. For my run with Mo/Me, I opted for Illusion instead of Inspiration because of the Burden spell, which does 10 damage a second and is often considered to be a good starting spell but later on gets broken easily. At that point I switched to Domination. The problem with being a Mo/Me with Domination is simply you don't have the time/energy to interrupt spells and hexes are usually killed off easily. Also, a drawback of most Dom spells is that they take a long (fairly) time to cast unless you have Fast Cast.
Realising all these (too late) I started a new char that is a Me/Mo and found him to be quite fun. The Mo skills coupled with fast cast can keep me alive, but I don't usually have the time to be a primary healer, maybe just a backup one. The initial set of skills are ok and don't do much damage, though but I'm looking forward to Chaos Storm which i believe to be a very good spell.
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