if you ball them up well and stand next to them they wont cast healing spring, however your problem was probably melandru's resilience each time you cast a hex on them they would regen.
It is pretty easy to kill them with the A/E lavafont build, however you may have energy problems, just make sure your health is under 100 so the driftwoods will not scatter. Don't use Mark of Rodgort on the spiders because it again triggers melandru's resilience.
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