what Afya said.
Spirit spam + 3 discord heroes for the quest "Every bit helps" if you intend to solo it yourself or you can just join a group.
Average time for a run of the opening area of the underworld is about 6-8 minutes and can get approx 30 skeletons in about an hour resulting in 250 ToT bags.
Just make sure to get as many mobstobbers you can from the steward so you can just do the run back to back. Also, as long as you cap more then 3 skeletons per run you can get extra platinum when turning in the quest.
Edit: Oh, aatxe and skeletons have a chance to drop ecto too.
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