Assassin's promise nuker builds are fun. Although very energy/exhaustion intensive. (I've been toying with the idea of a Me/E nuker with an assassin and ele, running AP, Symbols of Inspiration, and glyph of energy(Echo arcane mimicry)...)
Aside from that, do what I do when I want to have fun. Pick out 8 skills at random and 3 heroes/henchmen, go into hard mode and see how far you get. I actually managed to vanq almost all of Istan using this strategy, and pretty fast too (Average time: 2h/area).
You could also try a mirror of ice build. I hear those can be interesting.
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