Not sure there's any decent build that does it all, it's usually either melee shutdown, caster hate, or fast casting offensive spells. I'd probably go something along:
1. Illusion Mesmer with Psychic Instability and Arcane Conundrum + Earthbind on either mesmer or another hero. Ball up foes nearby when pulling, Knock Down 4 seconds and unleash a flurry of AE. An AE snare might be good.
2. Shared Burden for slowing attack/spells/movements by 50%, interrupts for shutting down healers or any foe with hex removal skills. Melee at 50% speed/attack for ~20 seconds while you take out casters shouldn't be much of a threat.
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